CTAB Extraction Buffer is a widely-used reagent used to isolate DNA from plant tissues. Polysaccharides and polyphenols are problematic contaminants associated with DNA isolated from plants. CTAB Extraction Buffer effectively eliminates polysaccharides and polyphenols by employing the cationic detergent CTAB (hexadecyltrimethylammonium bromide or cetyltrimethylammounium bromide), and the polyphenol binding agent, Polyvinylpyrrolidone. Traditional CTAB protocols typically require the homogenization of plant samples in CTAB Extraction Buffer prior to centrifugation to pellet debris and polysaccharides. The supernatant is then extracted using chloroform, and DNA is precipitated with alcohol. Isolated DNA is typically very clean. CTAB Extraction Buffer is quality-control tested for sterility and consistency. It is a cost-effective and time-saving alternative to purchasing reagents and formulating homegrown buffers. This ready-to-use formula is available in 125 ml and 500 ml bottles.