Mannitol Lyophilization Certified, 500 gm Size: 500 gm Product Number: OP-EXMN500-01 Mannitol serves as a matrix forming additive for lyophilization. When used at concentrations up to 10% w/v, mannitol forms an amorphous (non-crystaline) matrix which supports proteins and other biomolecules for freeze drying. It is generally inert and once freeze dried, rehydrates rapidly. It's amorphous structure while frozen prevents it from disrupting proteins while providing channels for water sublimation during processing. OPS Diagnostics mannitol is USP grade, with each batch being certified for lyophilization.